Saturday, November 22, 2014

Methamphetamine cardiomyopathy (MAC)

Here are some key points from a review:

MAC is a newly emerging entity and is somewhat poorly understood.

It appears to be mainly a dilated cardiomyopathy (systolic dysfunction).

It appears to be reversible upon cessation of the ingestion, acknowledging that there may be a point in time of irreversibility.

It is believed to be catecholamine mediated and as such has features in common with stress cardiomyopathy, including pathologic findings of contraction band necrosis.

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