Wednesday, July 29, 2015

Volume controlled versus pressure controlled ventilation in ARDS

Given that treatment needs to be individualized, there is insufficient evidence to tell whether one is better than the other across the board according to a Cochrane review.

Tuesday, July 28, 2015

Relationships between exercise, hunger and energy balance

Interesting article in the American Journal of Lifestyle Medicine:

High-intensity exercise causes a short-term suppression of hunger of approximately 15 to 60 minutes. Although there is evidence for compensatory food consumption, it usually does not make up for the energy deficit created by exercise. The exception occurs when individuals consume or reward themselves with energy-dense foods or drink. Because people tend to eat the same volume of food each day, on days when they exercise, they will remain in an energy deficit. However, on sedentary days, a positive energy balance is likely if caloric restriction is not imposed, which could result in weight gain. Caloric restriction alone leads to loss of lean body mass, while the inclusion of exercise with an energy deficit helps conserve lean tissue.

Monday, July 27, 2015

What’s new in the management of acute severe asthma?

From a recently published update:

Recent findings: β2-agonist heliox-driven nebulization significantly increased by 17% [95% confidence interval (CI) 5.2–29.4] peak expiratory flow, and decreased the rate of hospital admissions (risk ratio 0.77, 95% CI 0.62–0.98), compared with oxygen-driven nebulization. Other findings indicate that there is no robust evidence to support the use of intravenous or nebulized magnesium sulphate in adults with severe acute asthma, and that levalbuterol was not superior to albuterol regarding efficacy and safety in individuals with acute asthma. Finally, hyperlactatemia developed during the first hours of acute asthma treatment has a high prevalence, is related with the use of β2-agonists and had no clinical consequences.

Sunday, July 26, 2015

Exercise to improve cognitive function

This review focuses on the cognitive impairment associated with heart failure. Neurophysiologic mechanisms are discussed.

Saturday, July 25, 2015

When hypersensitivity pneumonitis enters the fibrotic stage

---it can mimic many other diffuse ILDs as outlined in this review.

Friday, July 24, 2015

Whole bowel irrigation for overdose patients

A recent literature review found that it may facilitate removal in selected patients but is not supported by convincing evidence of improved outcomes.

Thursday, July 23, 2015

Exercise as treatment for depression

Bottom Line Exercise is associated with a greater reduction in depression symptoms compared with no treatment, placebo, or active control interventions, such as relaxation or meditation. However, analysis of high-quality studies alone suggests only small benefits.